Technologies
Biomarker quantification at the femtogram level
Immunoassay at the femtogram level allows drug developers to detect very small changes in biomarkers concentrations.
Indicia Biotechnology addresses unmet needs in molecular diagnostic by offering a cutting edge technology that quantitatively detects biomarkers at the sub-picogram level.
The Erenna® Immunoassay System couples improved assay sensitivity and extended dynamic range compared to conventional immunoassay.
Indicia Biotechnology’s offer
Indicia Biotechnology provides:
- Customized assay development
- Bioanalytical method validation
- Sample analysis
Technology description
The Erenna Immunoassay System consists of two major steps: a modified microparticle based sandwich immunoassay followed by single-molecule counting technology.
The system integrates capillary flow, laser-induced fluorescence, a highly sensitive detection optics module, and a 384-well plate format for sample analysis.
The Erenna Immunoassay System incorporates a robust digital molecule-counting module to count photons, where ultra-sensitive fluorescence is measured in the presence of proprietary background reduction methodology.
A large dynamic range of 4+ logs is obtained by combining single-molecule counting (low range) with photon counting (mid range) and total light measurements (high range).
The Erenna Immunoassay System includes a fully equipped bench-top analytical instrument, a set of integrated and prepared reagents in micro-titer plate format, and data management software to automatically display detailed assay reports in a user-friendly format.
This reliable, easy-to-use, walk-away system produces results from biological specimens like serum or plasma.